Comparison of the Additive Effects of Intravenous Methyl Prednisolone with that of Intravenous Pentoxyfylline on Low Tidal Volume Normal Frequency Ventilation as a Lung Protection Strategy during Cardiopulmonary Bypass that Improves Immediate Postoperative Outcome
نویسندگان
چکیده
Postoperative pulmonary dysfunction is a common complication after cardiopulmonary bypass (CPB) [1]. Though there has been lots of improvement in the fields of surgery, perfusion and anesthesia in both skill and technologies during previous years, postoperative pulmonary complications cannot be avoided completely [2]. The ultimate outcome for all types of pulmonary complication is hypoxemia with its variations [3]; incidence of adult respiratory distress syndrome is 2% while incidence of atelectasis is 64% after CPB [4,5]. Postoperative lung dysfunction may even persist for weeks after cardiac Comparison of the Additive Effects of Intravenous Methyl Prednisolone with that of Intravenous Pentoxyfylline on Low Tidal Volume Normal Frequency Ventilation as a Lung Protection Strategy during Cardiopulmonary Bypass that Improves Immediate Postoperative Outcome
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اثـر تهویـه ریوی حین بـای پاس قلبـی ریوی بـر پیامدها و عـوارض ریوی پس از عمـل جراحی پیوند عـروق کرونر
Aim and background: Despite improved techniques of cardiopulmonary bypass and postoperative care, pulmonary dysfunction after CABG is still a major cause of postoperative morbidity. Different methods of pulmonary ventilation have been used for lung protection. But has not definite conclusions about the effects of these methods. The aim of this study was determining the effect of pulmonary vent...
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متن کاملThe Effect of Low Tidal Volume Ventilation during Cardiopulmonary Bypass on Postoperative Pulmonary Function
BACKGROUND Postoperative pulmonary dysfunction is one of the most frequent complications after cardiac surgery and it is believed to result from the use of cardiopulmonary bypass (CPB). In this study, we investigated the effect of low tidal volume ventilation during CPB on postoperative gas exchange and lung mechanics. METHODS This prospective randomized study included 100 patients undergoing...
متن کاملMethyl prednisolone and lung function after cardiopulmonary bypass.
Thirty-one patients who were undergoing cardiopulmonary bypass for elective aortic valve replacement were studied. The effects on some aspects of lung function of intravenous methyl prednisolone, administered immediately before bypass, were assessed by measuring alveolar-arterial oxygen differences and shunt fractions. No significant differences in pulmonary function were found between the trea...
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INTRODUCTION Cardiopulmonary bypass causes a series of inflammatory events that have adverse effects on the outcome. The release of cytokines, including interleukins, plays a key role in the pathophysiology of the process. Simultaneously, cessation of ventilation and pulmonary blood flow contribute to ischaemia-reperfusion injury in the lungs when reperfusion is maintained. Collapse of the lung...
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